Three Compartment Model with Absorption (Closed Form)

[Generated automatically as a Generation summary]

Model Description

Name:

dep_three_cmp_cl_anyl

Title:

Three Compartment Model with Absorption (Closed Form)

Author:

PoPy for PK/PD

Abstract:

Three Compartment Model with Absorption

Central compartment with 2 peripheral compartments and a depot.

Model uses a closed form solution.

Parameters are:-

* CL = elimination clearance from central compartment

* V1 = Volume of central compartment

* Q2 = Inter-compartmental clearance between central and first peripheral

* V2 = Volume of first peripheral compartment

* Q3 = Inter-compartmental clearance between central and second peripheral

* V3 = Volume of second peripheral compartment

Keywords:

three compartment model; dep_three_cmp_cl; advan12; trans4

Input Script:

dep_three_cmp_cl_anyl_gen.pyml

Diagram:

Outputs

Population simulated (sim) plots

	allOBS_vs_TIME
	indOBS_vs_TIME

Generated parameter .csv files

Fixed Effects:

fx_params.csv (gen)

Random Effects:

rx_params.csv (gen)

Model params:

mx_params.csv (gen)

State values:

sx_params.csv (gen)

Predictions:

px_params.csv (gen)

Observations:

synthetic_data.csv (gen)

Inputs

True f[X] values (for simulation)

(Model has no fixed effects)