Bioavailability and Lag
[Generated automatically as a Tutorial summary]
Model Description
- Name:
biolag_abs_lag
- Title:
Bioavailability and Lag
- Author:
PoPy for PK/PD
- Abstract:
One compartment model absorption dosing with bioavailability and lag parameters.
- Keywords:
identifiability; bioavailability; lag; dep_one_cmp_cl
- Input Script:
- Diagram:
Comparison
True objective value
44.2050
Final fitted objective value
38.5454
Compare Main f[X]
Name |
Initial |
Fitted |
True |
Abs. Error |
Prop. Error |
|---|---|---|---|---|---|
f[KA] |
0.5 |
0.984 |
0.3 |
6.84e-01 |
227.95% |
f[CL] |
1 |
0.882 |
3 |
2.12e+00 |
70.61% |
f[V] |
15 |
6.21 |
20 |
1.38e+01 |
68.96% |
f[BIO] |
0.8 |
0.274 |
1 |
7.26e-01 |
72.56% |
f[LAG] |
1 |
8.64 |
5 |
3.64e+00 |
72.88% |
Compare Noise f[X]
Name |
Initial |
Fitted |
True |
Abs. Error |
Prop. Error |
|---|---|---|---|---|---|
f[ANOISE_STD] |
5 |
0.893 |
1 |
1.07e-01 |
10.73% |
Compare Variance f[X]
No Variance f[X] values to compare.
Outputs
Fitted f[X] values (after fitting)
f[KA] = 0.9839
f[CL] = 0.8818
f[V] = 6.2090
f[ANOISE_STD] = 0.8927
f[BIO] = 0.2744
f[LAG] = 8.6439
Generated data .csv file
- Synthetic Data:
Gen and Fit Summaries
Gen: Bioavailability and Lag (gen)
Fit: Bioavailability and Lag (fit)
Inputs
True f[X] values (for simulation)
f[KA] = 0.3000
f[CL] = 3.0000
f[V] = 20.0000
f[ANOISE_STD] = 1.0000
f[BIO] = 1.0000
f[LAG] = 5.0000
Starting f[X] values (before fitting)
f[KA] = 0.5000
f[CL] = 1.0000
f[V] = 15.0000
f[ANOISE_STD] = 5.0000
f[BIO] = 0.8000
f[LAG] = 1.0000